Cold Atmospheric Plasma (CAP) is a state of matter known as the fourth state of matter, alongside solid, liquid, and gas, wherein a gas is ionized and energized to temperatures of up to 100,000 degrees or higher. In atmospheric pressure plasma discharge, electrons and particles may be in thermal non-equilibrium, with the heavy particle temperature being much lower than that of the electrons. This type of plasma, known as cold atmospheric plasma (CAP), has a heavy particle temperature ranging from 25°C to 45°C, and is commonly used in biomedicine.

The Plasma Design of the Human Regenerator JET, also known as HIP, is even softer and has smaller particles compared to CAP, as seen in CAP Plasma Pens used in dermatology. This softer design with smaller particles enables HIP to reach deeper tissues within the body and perform similar cell regenerative activities as Plasma Pens do on the surface of the skin. Moreover, the Human Regenerator JET treats the entire body at once, instead of targeting a single point on the skin like Plasma Pens.